Jaspriya Sandhu; Sunil Kumar Gupta; Shriya Garg; Sheerin Shah; Bhavna Garg
Abstract
Bowen’s disease (BD) is an in situ squamous cell carcinoma ofthe skin. Pigmented Bowen’s disease (pBD) is a rare variant,representing less than 2% of all BD cases. We report a case ofGiant pBD arising from seborrheic keratosis in a 65-year-old man.The dermoscopy showed a scaly surface, structureless ...
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Bowen’s disease (BD) is an in situ squamous cell carcinoma ofthe skin. Pigmented Bowen’s disease (pBD) is a rare variant,representing less than 2% of all BD cases. We report a case ofGiant pBD arising from seborrheic keratosis in a 65-year-old man.The dermoscopy showed a scaly surface, structureless brown togrey-black areas with dotted vessels, glomerular and reticulatevessels, and a few brown globules. Histopathology was classicalwith a “windblown appearance”; prominent melanophages wereseen in the dermis. Owing to the size and thickness of the plaque,a wide excision with a split-skin graft was done. The graft uptakewas good, and the patient was followed up on days 4 and 26post-surgery. We present our experience with the diagnosis andmanagement of this rare case of giant pBD. To the best of ourknowledge, such a case has not been previously reported.
Iffat Hassan; Peerzada Sajad; Syed Mubashir
Volume 17, Issue 3 , 2014, , Pages 101-103
Abstract
Background: Bowen’s disease is a form of intraepidermal squamous cell carcinoma (SCC) characterised by a persistent, non-elevated, red, scaly or crusted plaque with a small potentialfor invasive malignancy. Most cases of typical Bowen’s disease in the white population are found ...
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Background: Bowen’s disease is a form of intraepidermal squamous cell carcinoma (SCC) characterised by a persistent, non-elevated, red, scaly or crusted plaque with a small potentialfor invasive malignancy. Most cases of typical Bowen’s disease in the white population are found on the lower legs of the elderly women. However, in this part of the world, i.e. Kashmir, the mostcommon site is thighs followed by the lower abdomen. A range of treatment options are available for it including cryotherapy, curettage and cautery, photodynamic therapy, laser destruction,surgical excision, 5-fluorouracil cream, imiquimod cream, and radiotherapy. The aim of this study was to evaluate the efficacy of surgical excision in Bowen’s disease.Method: All the patients with biopsy proven Bowen’s disease were included for the study. A detailedhistory was taken for each patient including the history of medical treatment for Bowen’s disease. Wide surgical excision (including either fusiform excision, W-plasty, or Z-plasty) was performed in each patient and the patients were then followed up for any recurrence. No sign of renewed disease activity at 6 months follow-up was taken as cure. All patients are intended to be followed up for 5 years.Result: Ten out of 12 patients reported the use of topical imiquimod cream but complained of the progression of lesions. Surgical excision was performed in 12 patients. All the patients are currently under regular follow-up. Except for secondary infection and wound dehiscence in one patient, all the patients are in good condition with no signs of recurrence.Conclusion: Although it was a preliminary study, we recommend surgical excision in treatment of Bowen’s disease due to low recurrence rate.
Meibodi Naser Tayyebi; Nahidi Yalda; Javidi Zari; Taheri Ahmad Reza; Jahanfakhr Monavar Afzalaghaee Samaneh
Volume 15, Issue 3 , 2012, , Pages 89-94
Abstract
Background: Precancerous lesions are disorders that are highlylikely to become malignant. Early diagnosis of precancerous skinlesions helps to prevent skin cancers. The aim of this study wasclinicopathological assessment of precancerous skin lesions inpatients referred to the dermatology department of ...
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Background: Precancerous lesions are disorders that are highlylikely to become malignant. Early diagnosis of precancerous skinlesions helps to prevent skin cancers. The aim of this study wasclinicopathological assessment of precancerous skin lesions inpatients referred to the dermatology department of Imam Rezahospital.Method: Two hundred and nine patients who were diagnosed withprecancerous lesions and referred to the dermatology departmentof Imam Reza hospital from 1997 to 2007 were studied. Studyparameters included participants’ age, sex and occupation, typeof precancerous skin lesion, clinicopathological type of the lesionand location. The data was collected from the patients’ recordsin the dermatology department and their microscopic slides inthe pathology department.Result: The most common precancerous skin lesion was actinickeratosis (68.4%) followed by Bowen’s disease (7.2%). About67.5% of the patients were male with a mean age of 61.7 years.Moreover, 53.1% of the patients worked outdoors. The mostcommon site of the lesions was head and neck (83.3%) and 18.7%of lesions were associated with malignancy. The most commonpathological form of actinic keratosis was the proliferative type(28.9%).Conclusion: The results of this study showed that precancerousskin lesions were more prevalent in men aged over 50 years, insun-exposed areas and in occupations practiced outdoors. Inaddition to squamous cell carcinoma, these lesions could alsobe associated with basal cell carcinoma.