P Toosi; A Sadiqha; H Monshi Zadeh; R Toosi
Volume 8, Issue 4 , 2005, , Pages 256-259
Abstract
Background and objective: Oral isotretinoin is the only treatment that has an effect on all the major etiological factors involved in acne (Increased sebum production, alterations in microbial flora, hyperkeratinization of pilosebaceous duct, and inflammation). Considering complications and relative ...
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Background and objective: Oral isotretinoin is the only treatment that has an effect on all the major etiological factors involved in acne (Increased sebum production, alterations in microbial flora, hyperkeratinization of pilosebaceous duct, and inflammation). Considering complications and relative expense, several treatment regimens have been suggested. The objective of this study was to evaluate the efficacy of intermittent doses of isotretinoin in acne patients. Materials ad Methods: We made a quasi-experimental clinical trial in the acne patients without nodular and cystic lesions that were recalcitrant to conventional therapy. Therapeutic regimen included 0.5 mg/kg isotretinoin per day for a week every month; So we use 21 mg/kg as total dosage. Results: Acne severity decreased in entire patients at the end of treatment course. After six months follow up, recurrence rate was 19.3% and partially recurrence rate was 44%. Conclusion: It seems that intermittent isotretinoin treatment with a total dose of 21 mg/kg has led to good therapeutic results in patients without nodulocystic lesions.
P Toosi; F Malekzad; A Sedigha
Volume 8, Issue 1 , 2004, , Pages 7-14
Abstract
Background: The theory of selective photo-thermolysis led to the development of a variety of different laser systems which range from the shorter spectrum of 694nm ruby laser to the middle with the 755nm alexandrite and 810nm diode lasers to the long end with the 1064nm (Nd:YAG) laser. Objective: A systematic ...
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Background: The theory of selective photo-thermolysis led to the development of a variety of different laser systems which range from the shorter spectrum of 694nm ruby laser to the middle with the 755nm alexandrite and 810nm diode lasers to the long end with the 1064nm (Nd:YAG) laser. Objective: A systematic review on the clinical trials with use of various laser sources for hair removal. Methods: All clinical trials related to hair removal lasers in 1998-2003 were selected. After elimination of heterogenicity sources in data, results were synthesized on the basis of laser type and were compared using ANOVA and t tests, P
P Toosi; F Hosseinzadeh; M Rahmati Roodsari; L Gachkar; Sh Manighalam
Volume 7, Issue 4 , 2004, , Pages 231-236
Abstract
Background: Various environmental factors can induce or exaggerate hand eczema. Objective: Evaluation of patch test results in hand eczema patients. Patients and Methods: In this descriptive study 100 patients with hand eczema referred to Loghman Hakim and Booali Hospital in Tehran underwent patch testing ...
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Background: Various environmental factors can induce or exaggerate hand eczema. Objective: Evaluation of patch test results in hand eczema patients. Patients and Methods: In this descriptive study 100 patients with hand eczema referred to Loghman Hakim and Booali Hospital in Tehran underwent patch testing with 23 allergens obtained from Hermal company. Results: 240 positive reactions observed in 86 patients. The most common positive reactions were related to nickel sulfate (30 patients, 13.5%) and potassium dichromate (28 patients, 11.7%). In positive group 28 patients were male and 58 were female. In negative group 3 patients were male and 11 were female (P>0.05). The mean age was 31.7±11.9 years and 24.8±9.2 years for positive group and negative group, respectively (P0.05). Conclusion: Performing patch test, the allergens involved in hand eczema can be detected. Detecting type of allergens, patients will be able to avoid those materials, which can lead to improvement of disease.
P Toosi; L Gachkar; M Rostami Moghaddam
Volume 5, Issue 4 , 2002, , Pages 28-31
Abstract
Background: The prevalence of Helicobacter pylori (H. pylori) infection in patients with rosacea is reported from 50 to 90 percent, which suggests the possibility of the role of this organism in pathogenesis of rosacea. Objectives: Evaluation of relationship between H. pylori infection and rosacea. Patients ...
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Background: The prevalence of Helicobacter pylori (H. pylori) infection in patients with rosacea is reported from 50 to 90 percent, which suggests the possibility of the role of this organism in pathogenesis of rosacea. Objectives: Evaluation of relationship between H. pylori infection and rosacea. Patients and Methods: In this case-control study, 30 patients referred to skin clinics of Boo-Ali and Loghman Hakim hospitals in Tehran were compared with 30 individuals of similar sex and age who had not rosacea (Control group). Serologic tests for H. pylori infection (IgG and IgA), and also urea breath test were done. The results were compared using chi-square test with 95% confidence interval and P<0.05 was considered as significant. Results: No significant differences were seen between patients with rosacea and control group in having IgA (60% in case group, 40% in control group), IgG (76.6% in case group, 53.3% in control group) and positive breath test. Conclusion: More extensive research about possible relationship between H. pylori infection and rosacea is recommended.
