Armaghan Ghareh Aghaji Zare; Afsaneh Radmehr; Sara Saniee; Mohadese Dalvand; Mohammad-Salar Hosseini
Abstract
Background and Aim: Autoimmune Bullous Diseases (AIBDs) are characterized by blistering skin and mucous membrane lesions. This study evaluated the quality of life and associated factors in patients with AIBDs.Methods: In this cross-sectional study, we included all clinicallyand laboratory-confirmed AIBD ...
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Background and Aim: Autoimmune Bullous Diseases (AIBDs) are characterized by blistering skin and mucous membrane lesions. This study evaluated the quality of life and associated factors in patients with AIBDs.Methods: In this cross-sectional study, we included all clinicallyand laboratory-confirmed AIBD patients older than 16 years who sought care at the Dermatology and Hair Clinic of Sina Hospital (Tabriz, Iran) from March to September 2020. We collected the demographic characteristics, disease profile, Autoimmune Bullous Disease Quality of Life (ABQOL) score, and Autoimmune Bullous Skin Disorder Intensity Score (ABSIS). The recorded data were analyzed using SPSS v16 software.Results: One hundred patients (44 men and 46 women) with a mean age of 52 ± 2 years participated in this study. Among them, 76 had pemphigus vulgaris, 18 had bullous pemphigoid, and 6 had pemphigus foliaceous. A median score of six was recorded for the ABQOL, and a median score of one was recorded for the ABSISscale. The relationship between quality of life and disease severity was statistically significant (P = 0.001). Also, a weak but statistically significant association was observed between the quality of life and patients’ age (P = 0.049).Conclusion: We demonstrated that increased disease severity significantly impairs AIBD patients’ quality of life. On this account, patients with severe AIBDs require more social, psychological, and financial support.
Anu George T; Vinutha Rangappa; Jayadev Betkerur
Abstract
Background: Periorbital hyperpigmentation (POH), a common problem of multifactorial etiology, is obvious on the face and can affect patients’ quality of life (QoL). It is essentially a clinical diagnosis, but dermoscopy might aid in further classification of the disease. Also, it might give us ...
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Background: Periorbital hyperpigmentation (POH), a common problem of multifactorial etiology, is obvious on the face and can affect patients’ quality of life (QoL). It is essentially a clinical diagnosis, but dermoscopy might aid in further classification of the disease. Also, it might give us a clue regarding the etiology and help in the treatment, as different types of POH respond to varying treatments. We aimed to assess clinical, dermoscopic patterns and quality of life using the Melasma Quality of Life (MELASQOL) scale in POH and to compare it with controls.Methods: Detailed histories were obtained from 100 patients with POH. The clinical and dermoscopic examination was done, and the obtained results were compared against 100 controls. The MELASQOL scale was used to assess QoL.Results: Family history (P = 0.013), lack of sleep (P = 0.003), stress (P = 0.001), and eye rubbing (P = 0.01) were the probable risk factors. Blotchy pattern (P < 0.0001), speckled pattern (P < 0.0001), and telangiectasia (P = 0.007) were the significant dermoscopic findings. Controls showed pseudoreticular (P < 0.001) and superficial dilated veins (P < 0.0001). Quality of life was affected in 30.6% of patients; it was more affected in grade 4 POH.Conclusion: Dermoscopy will aid in the classification of POH. Blotchy pattern, speckled pattern, and telangiectasia are the typical dermoscopic patterns, more so in higher grades. QoL may be affected in POH. However, MELASQOL is not adequate to assess QoL in POH.
Abdul Malik Hooshmand; Nasar Ahmad Shayan
Abstract
Background: Vitiligo is a chronic pigmentary disorder of the skin. Although predominantly asymptomatic and not life-threatening, vitiligo may considerably affect patients’ quality of life (QoL). It has been suggested that vitiligo patients suffer from low selfesteem and poor body image, which may ...
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Background: Vitiligo is a chronic pigmentary disorder of the skin. Although predominantly asymptomatic and not life-threatening, vitiligo may considerably affect patients’ quality of life (QoL). It has been suggested that vitiligo patients suffer from low selfesteem and poor body image, which may cause a lower level of QoL. The objective of this study was to evaluate the effect of vitiligo on patients’ QoL in Herat, Afghanistan.Methods: This descriptive study was conducted at Hooshmand Skin and Cosmetic Hospital and the associated phototherapy center from November 2015 to April 2017. A total of 170 patients above 16 years of age were recruited. A valid translated Persian version of the Dermatology Life Quality Index (DLQI) was completed by subjects, and data were collected using structured datasheets.Result: On average, patients were 27.84 ± 10.74 years old, and 40.6% were males. The overall mean DLQI score was 9.72 ± 5.82, including 9.93 ± 4.64 in women and 9.42 ± 6.11 in men. The DLQI score was significantly related to the age, type of disease, treatment history, and employment status. Compared to males’, females’ QoL was more impaired in feeling (Q2) and type of clothing (Q4) (P = 0.020 and P = 0.021, respectively).Conclusion: Vitiligo patients showed a moderate limitation in their QoL. Hence, the managing team should focus on the QoL and psychosocial well-being of vitiligo patients in addition to their clinical condition.
Mojgan Karbakhsh; Kosar Hedayat; Azadeh Goodarzi; Maryam Ghiasi; Narges Ghandi
Abstract
Background: Vitiligo is a stigmatizing, chronic, and usually progressive skin disorder that affects patients' quality of life and can interfere with their social participation. There are no studies in developing countries focusing on this aspect. Hence, we assessed social participation in patients with ...
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Background: Vitiligo is a stigmatizing, chronic, and usually progressive skin disorder that affects patients' quality of life and can interfere with their social participation. There are no studies in developing countries focusing on this aspect. Hence, we assessed social participation in patients with vitiligo and its associations with Vitiligo Quality of Life (VitiQoL), Vitiligo Area Score Index (VASI), and demographic and clinical characteristics. Methods: This cross-sectional study was conducted between 2013-2014 on 170 patients, in Razi Hospital, Tehran, Iran. In the pilot phase, the Persian version of the Participation Scale (P-scale) and VitiQoL questionnaire were validated with the backward-forward translation method. Results: Among 173 vitiligo patients, the mean participation score was 15.12 (SD=13.88, median=11). Overall, 91 patients (52.6%) had no significant restriction, 38 (22%) suffered from mild, 23 (13.3%) moderate, 20 (11.6%) severe, and 1 (0.6%) suffered from extreme restriction in participation. The association between VitiQol and P-scale was highly significant (r=0.58; p <0.001). This association was also observed with the three subscales of VitiQol, namely participation limitation (r=0.59, p <0.001), behavior (r=0.43, p <0.001), and stigma (r=0.23, P=0.002). We did not find a significant association between P-scale and demographic characteristics, overall VASI, and face, genitals, and exposed areas VASI. Conclusion: Although the majority of our patients perceived no or mild limitation in their social participation, the P-scale score was highly correlated with their quality of life and its components.
Hojat Eftekhari; Seyyede Zeinab Azimi; Abbas Darjani; Rana Rafiei; Melika Amookhteh
Abstract
Background: Psoriasis is a chronic disease that may affect patients’ quality of life. We investigated the quality of life (QoL) and its related factors in psoriasis patients. Methods: In this cross-sectional study, 123 patients with psoriasis vulgaris were enrolled, who were at the ...
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Background: Psoriasis is a chronic disease that may affect patients’ quality of life. We investigated the quality of life (QoL) and its related factors in psoriasis patients. Methods: In this cross-sectional study, 123 patients with psoriasis vulgaris were enrolled, who were at the age of 18-55 years. The QoL was assessed by the psoriasis disability index (PDI) questionnaire. The stress associated with psoriasis was evaluated by the psoriasis life stress inventory (PLSI) questionnaire. The severity of the disease (SoD) was measured based on the psoriasis area and severity index (PASI) score. Results: In this study, the mean age of the patients was 40.77 ± 0.73 years, and the mean duration of the disease was 8.7 ± 8.23 years. The average PASI score was 11.06, and the average PDI score was 11.98. The average PDI and PASI scores of smoker patients were significantly more than those of non-smokers (P = 0.017). There was a strong relationship between all parts of QoL and PLSI scores, as well as between PASI and PLSI (P < 0.05). Conclusions: Psoriasis reduced our patients’ quality of life. Thus, it is recommended that the QoL in psoriatic patients be evaluated. Stress management and psychological supporting methods are necessary for these patients.
Triana Agustin; Githa Rahmayunita; Rinadewi Astriningrum; Eliza Miranda; Erdina HD Pusponegoro; Sandra Widaty
Abstract
Background: Seborrheic dermatitis (SD) is an inflammatory disease affecting seborrheic areas of the skin. Scalp SD varies from mild, manifesting as dandruff, to erythematous lesions with greasy scales. SD negatively affects patients’ quality of life.Methods: This is a cross-sectional study investigating ...
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Background: Seborrheic dermatitis (SD) is an inflammatory disease affecting seborrheic areas of the skin. Scalp SD varies from mild, manifesting as dandruff, to erythematous lesions with greasy scales. SD negatively affects patients’ quality of life.Methods: This is a cross-sectional study investigating the relationship between quality of life and disease severity in patients with dandruff and scalp SD at the Dermatology and Venereology Outpatient Clinic, of Dr. Cipto Mangunkusumo General Hospital. SD severity was assessed by the modified Seborrheic Dermatitis Area and Severity Index (SDASI), and quality of life was assessed by the Indonesian version of the Dermatology Life Quality Index (DLQI).Results: A total of 96 subjects with scalp SD were recruited, comprising 86 subjects with mild SD and 10 subjects with moderate SD. DLQI scoring revealed 5 subjects (5%) felt no effect of SD at all on their lives, 10 subjects (10%) felt small effect, 38 subjects (40%) felt moderate effect, 32 subjects (33%) felt very large effect, and 2 subjects (2%) felt extremely large effect on their lives. There is no significant difference between SD severity with the average DLQI score in the mild SD group (8.73 ± 4.9) and the moderate SD group (9.30 ± 6.13), P=0.737. Furthermore, no significant difference was found between the DLQI scores in the male (9.86 ± 4.7) and female (8.18 ± 5.13) groups, P=0.116. Spearman’s correlation analysis revealed no significant relationship between age and DLQI scores (r=-0,104, P=0,313).Conclusions: Our study concludes that SD negatively affects the quality of life.
Abedini Robabeh; Lajevardi Vahideh; Hallaji Zahra; Khodashenas Zohre; Zafar Fatemeh; Nasimi Maryam
Volume 19, Issue 4 , 2016, , Pages 113-118
Abstract
Background: Psoriasis is a chronic skin disorder that can significantly affect a patient’s quality of life (QoL). The goal of this study was to determine the QoL in patients with psoriasis and to investigate the correlation between the QoL, demographic data, and clinical severity of psoriasis.Methods: ...
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Background: Psoriasis is a chronic skin disorder that can significantly affect a patient’s quality of life (QoL). The goal of this study was to determine the QoL in patients with psoriasis and to investigate the correlation between the QoL, demographic data, and clinical severity of psoriasis.Methods: This prospective, cross-sectional study was conducted from April 2014 to January 2015. One hundred patients with plaque type psoriasis from the Phototherapy Clinic of Razi Hospital, Tehran, Iran were selected and asked to complete questionnaires. The Psoriasis Area Severity Index (PASI) to measure the severity of psoriasis, and the Dermatology Life Quality Index (DLQI) was used for the assessment of the quality of life.Results: The total DLQI score of the all participants was between 0 and 29 with a mean score of 10.6 ± 6.4. The DLQI scores ranged from “very large” to “extremely large” in 45% of the patients. The mean score was 9.2 ± 6.6 in the male group and 12.1 ± 5.9 in the female group, which showed a statically significant difference (P=0.02). Other variables associated with an impaired QoL were age (P=0.002) and PASI (P=0.01). The impact on QoL was higher in younger patients, and in patients with higher PASI scores.Conclusion: In conclusion, although psoriasis is a benign disorder, this study confirms our initial hypothesis that psoriasis significantly impairs the QoL, which is more pronounced in younger patients, women, and patients with a more severe disease (higher PASI scores).
Handjani Farhad; Kalafi Amir
Volume 16, Issue 4 , 2013, , Pages 128-131
Abstract
Background: Chronic skin diseases such as vitiligo and psoriasis can impair the quality of life in the patients with these diseases. The impact of chronic and/or severe skin diseases on the lives of family members of the affected patients has only recently been addressed. The tool used for this assessment ...
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Background: Chronic skin diseases such as vitiligo and psoriasis can impair the quality of life in the patients with these diseases. The impact of chronic and/or severe skin diseases on the lives of family members of the affected patients has only recently been addressed. The tool used for this assessment is the Family Dermatology Life Quality Index (FDLQI). The aim of this study was to use the FDLQI to assess the impact of four skin diseases (pemphigus, psoriasis, vitiligo, and cutaneous leishmaniasis) on family members of the affected patients.Method: Fifty healthy family members of 50 patients with pemphigus, psoriasis, vitiligo, and cutaneous leishmaniasis were included in this study. The patients had to have an extensive disease with disease duration of at least one month. One family member of each patient completed the 10- item Persian version of the FLDQI questionnaire. The score of this index ranged from 0 to 30.Result: The mean duration and mean FDLQI score of the diseases were as follows: psoriasis (mean duration=4.1±2.7, mean FDLQI score=14.7±5.01), pemphigus (mean duration=3.6±2.3, mean FDLQI score=15.4±4.7), vitiligo (mean duration=5.1±4.05, mean FDLQI score=14.4±5.08) and cutaneous leishmaniasis (mean duration=0.62±0.23, mean FDLQI score=12.0±4.3). There was no significant difference among the groups (p=0.562). In addition, no strong correlation was observed between the mean duration of the disease and mean FDLQI scores for each condition (r=0.051, p=0.726).Conclusion: This small-scale study demonstrated that although not statistically significant, inflammatory diseases like pemphigus had a higher FDLQI score when compared to non-inflammatory conditions like vitiligo and short-term conditions such as leishmaniasis.
Mahsa Ghajarzadeh; Maryam Ghiasi; Shahrbanoo Kheirkhah
Volume 14, Issue 4 , 2011, , Pages 140-143
Abstract
Background: Alopecia Areata (AA) is a skin disease which affects 0.2 % of general population. Unlike its little physical impairment, Alopecia areata causes a lot of cosmetic problems but most clinicians do not pay attention to mood disorders and the impaired quality of life as the consequences of disease. ...
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Background: Alopecia Areata (AA) is a skin disease which affects 0.2 % of general population. Unlike its little physical impairment, Alopecia areata causes a lot of cosmetic problems but most clinicians do not pay attention to mood disorders and the impaired quality of life as the consequences of disease. Objectives: To evaluate depression and quality of life in Iranian patients with Alopecia areata . Methods: From January 2009 until January 2010 one hundred alopecia areata patients who were randomly selected (through simple random selection) from the outpatient clinic of Razi Hospital were asked to answer valid and reliable instruments such as Beck Depression Inventory (BDI), SF-36 and DLQI (Dermatology Life Quality Index) questionnaires. Results: The mean scores of BDI, SF-36and DLQI of the patients were 14.4±9.7, 68.04 ±15.1 and 6.4±5.5, respectively. The BDI score was significantly different between male and female participants (F=18.1 ±11.2 vs. M=12.7±8.5, p=0.01) but SF -36 and DLQI scores did not significantly differ between the two gender groups. Duration of the disease, BDI and age had no significant correlation with DLQI scores. Patients with extensive beard involvement had the highest BDI score and the lowest SF-36 score. Conclusion: mood disorders should be considered in Alopecia areata patients to address the risk of markedly impaired quality of life
Javidi Zari; Tayyebi-Maybodie Naser; Taheri Ahmad Reza; Nahidi Yalda
Volume 10, Issue 4 , 2007, , Pages 309-315
Abstract
Background and aim: Psoriasis is a dermatologic disease which not only involves the patient physically, but also affects patient's quality of life. Due to its life time duration and psychologic burden, we decided to evaluate patient's quality of life using psoriasis disability index (PDI). Materials ...
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Background and aim: Psoriasis is a dermatologic disease which not only involves the patient physically, but also affects patient's quality of life. Due to its life time duration and psychologic burden, we decided to evaluate patient's quality of life using psoriasis disability index (PDI). Materials and methods: From August 2006 till March 2007, 80 patients referring to Imam-Reza dermatology clinic completed the PDI questionnaire and a demographic questionnaire. Collected data were analyzed by t-test, one way ANOVA tests using SPSS software. Results: 46.2% of patients were male and 53.8% female. The mean age of patients was 40.2 years. 10% had positive family history of psoriasis. 47.5% had a history of hospitalization. 41.3% had articular and 53.8% had nail involvement. Mean morbidity duration was 12.6 years and mean PDI score was 17.4±10 (maximum and minimum scores: 37 and 1 respectively). There was significant difference in mean PDI score in groups considering age, sex, education, location, duration and extent of disease, hospitalization history, nail involvement and type of treatment. Most disability was seen in the treatment field (both sexes) and occupation /school (men) and least disability was seen in individual relationships.Discussion: Psoriasis can reduce the patient's quality of life and satisfaction severely. Therefore supportive strategies can improve their quality of life.
AR Firooz; M Rashighi Firoozabadi; B Ghazi Saidi; Y Dowlati
Volume 4, Issue 3 , 2001, , Pages 11-17
Abstract
Background: Alopecia areata (AA) is a common disease with an unknown etiology. It is a chronic disease with causes severe disfigurement. So it may significantly affect the patients’ quality of life (QOL). This study was designed to evaluate illness perception and QOL in patients with AA. Patients ...
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Background: Alopecia areata (AA) is a common disease with an unknown etiology. It is a chronic disease with causes severe disfigurement. So it may significantly affect the patients’ quality of life (QOL). This study was designed to evaluate illness perception and QOL in patients with AA. Patients and Methods: A questionnaire consisting of 28 questions about causes, course and the impact on QOL were given to patients with AA older than 12 years attending a private skin clinic in 1999 in Tehran. The questions were asked as closed questions and the patients answered them anonymously as “I agree”, “I do not know” and “I disagree”. Only questionnaires with more than 80% of questions answered were analyzed. The role of age, sex, duration, previous treatment, education, severity and family history of AA were assessed. Results: 80 patients (42 male and 38 female) with a mean age of 27.5±9.3 years and disease duration of 7.8±7.7 years entered the study. 60 of them had AA and 20 had alopecia totalis/universalis (AT/AU). 77% of patients believed on the role of stress as the cause of disease, more in older patients and shorter duration. 17% believed on the role of genetic background, more in patients with positive family history of AA or longer duration of disease. AA had a pronounced effect on QOL of 58% of patients, more in younger patients. 51% of patients considered their disease as severe, more in younger patients or severe disease. Only 58% of patients considered their treatments effective and 49% of them believed it will improve with praying. Conclusion: AA may considerably affect various aspects of patients’ lives. The knowledge of patients about the causes and course of this disease is very limited. Physicians should spend more time on the education of patients.
